BDBM173610 9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]N6-benzoyladenine (11a)

SMILES OC[C@H]1O[C@H](C(O)[C@H]1n1cc(Cn2ccc(=O)[nH]c2=O)nn1)n1cnc2c(NC(=O)c3ccccc3)ncnc12

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173610   

TargetRibonuclease pancreatic(Bison bison (American bison))
University Of Thessaly

LigandPNGBDBM173610(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  5.55E+4nM ΔG°:  -5.90kcal/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-secretory ribonuclease(Homo sapiens (Human))
University Of Thessaly

LigandPNGBDBM173610(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  2.67E+5nM ΔG°:  -4.95kcal/mole IC50:  4.09E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed