BDBM179474 US9675697, Cpd. No. 25

SMILES COc1cc6c(cc1c2c(C)noc2C)[nH]c5ccnc(c3c(C)[nH]nc3c4ccccc4)c56

InChI Key InChIKey=ZJTYXGWJNWESQV-UHFFFAOYSA-N

Data  6 KI  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 179474   

TargetBromodomain-containing protein 3 [51-123](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2 [364-436](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 2 [91-163](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  41nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 3 [326-398](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  42nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
University of Michigan

US Patent
LigandPNGBDBM179474(US9675697, Cpd. No. 25)
Affinity DataKd:  60nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent