BDBM19473 2-Oxopropanoate::2-oxopropanoic acid::Pyruvate

SMILES CC(=O)C(O)=O

InChI Key InChIKey=LCTONWCANYUPML-UHFFFAOYSA-N

Data  4 KI  3 IC50  2 ITC

PDB links: 242 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19473   

TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Show SMILES CC(=O)C(O)=O
Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
TargetC-terminal-binding protein 2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Show SMILES CC(=O)C(O)=O
Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
Show SMILES CC(=O)C(O)=O
Show InChI InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19473   

CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔG°: 7.20kcal/mole −TΔS°: 8.57kcal/mole ΔH°: -1.37kcal/mole logk: 6.40E+3
pH: 7.4 T: 25.00°C 
CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔH°: -5.79kcal/mole logk: 3.10E+3
pH: 7.4 T: 25.00°C