BDBM202780 US10245267, Example 127::US10709712, Example 127::US9242969, 127::US9694016, 127

SMILES COc1ncc(cc1N1CCOCC1)-c1cc(NC(=O)c2cccc(c2)C(F)(F)F)cnc1C

InChI Key InChIKey=BSUIIPUXGLKINZ-UHFFFAOYSA-N

Data  16 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 202780   

TargetSerine/threonine-protein kinase B-raf(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 202780BDBM202780(US9694016, 127 | US9242969, 127 | US10245267, Exam...)
Affinity DataIC50: 1.67nMpH: 7.5 T: 2°CAssay Description:Final assay conditions were 4 pM cRaf, 3 uM ATP, 10 nM biotin tagged MEK1 kinase dead protein substrate. Reactions were performed in Greiner384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2016
Entry Details
US Patent