BDBM205423 US9243020, 17::US9815861, Example 17

SMILES CNC1=N[C@H]2[C@H](O[C@H](CF)[C@@H](O)[C@@H]2O)S1

InChI Key InChIKey=DJQLZCGDQCJIBK-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205423   

TargetProtein O-GlcNAcase(Human)
Alectos Therapeutics

US Patent
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataEC50:  34nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetProtein O-GlcNAcase(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM205423(US9243020, 17 | US9815861, Example 17)
Affinity DataEC50:  34nMAssay Description:Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed