BDBM221969 US9303035, 3.1

SMILES Cn1c2c3C(NCCn3c(-c3cccc(Cl)c3)c2c(=O)n(C)c1=O)c1ccc(Cl)o1

InChI Key InChIKey=AQRRSZYKWWEJTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221969   

TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221969(US9303035, 3.1)
Affinity DataIC50: 0.700nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In DepthDetails
US Patent