BDBM225529 GTC000235A

SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F

InChI Key InChIKey=AAMIJOPUOOWLFX-UHFFFAOYSA-N

Data  3 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225529   

TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225529(GTC000235A)
Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F
Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)
Affinity DataIC50: 9.64nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225529(GTC000235A)
Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F
Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)
Affinity DataIC50: 1.64nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225529(GTC000235A)
Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F
Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)
Affinity DataIC50: 1.94nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed