BDBM225531 GTC000237A::GTC000237B

SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F

InChI Key InChIKey=MDJFSTAJABJNCR-UHFFFAOYSA-N

Data  6 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 225531   

TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 1.87nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 6.87nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 2.75nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 3.14nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 8.63nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225531(GTC000237A | GTC000237B)
Show SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3[nH]c(=O)[nH]c3c2)ncc1F
Show InChI InChI=1S/C20H17FN8O/c1-2-29(17-5-3-4-14-12(17)9-23-28-14)18-13(21)10-22-19(27-18)24-11-6-7-15-16(8-11)26-20(30)25-15/h3-10H,2H2,1H3,(H,23,28)(H,22,24,27)(H2,25,26,30)
Affinity DataIC50: 3.76nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed