BDBM225538 GTC000242A

SMILES CCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3c(C)nn(CCCO)c3c2)ncc1F

InChI Key InChIKey=OXVVYSMZECGFOP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 225538   

TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225538(GTC000242A)
Affinity DataIC50:  3.61nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225538(GTC000242A)
Affinity DataIC50:  9.62nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225538(GTC000242A)
Affinity DataIC50:  3.88nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225538(GTC000242A)
Affinity DataIC50:  2.77nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225538(GTC000242A)
Affinity DataIC50:  1.58nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed