BDBM225562 GTC000266A::GTC000266B::GTC000266C

SMILES Cn1ncc2ccc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)cc12

InChI Key InChIKey=OZSNRTJXOLCWMK-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 225562   

TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  9.27nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  5.36nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  8.41nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  13.1nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  8.05nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  2.03nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  13.3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  1.30nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  8.41nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  4.49nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  11.3nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  8.18nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase SYK [355-635](Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM225562(GTC000266A | GTC000266B | GTC000266C)
Affinity DataIC50:  11.2nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed