BDBM23447 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide::Chloramphenicol::Chlornitromycin::Chloromycetin

SMILES OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=WIIZWVCIJKGZOK-UHFFFAOYSA-N

Data  1 KI  5 IC50  1 EC50  3 ITC

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23447   

TargetMethionine--tRNA ligase, mitochondrial(Human)
University of Washington

Curated by ChEMBL

LigandBDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)Copy SMILESCopy InChI

Affinity DataEC50:  7.90E+3nMAssay Description:Inhibition of mitochondrial MetRS-mediated mitochondrial protein synthesis in human HepG2 cells measured after 6 days by ELISAMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseDrugBankKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
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