BDBM23447 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide::Chloramphenicol::Chlornitromycin::Chloromycetin

SMILES OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=WIIZWVCIJKGZOK-UHFFFAOYSA-N

Data  1 KI  5 IC50  1 EC50  3 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23447   

TargetCytochrome P450 3A4(Human)
University of California At Santa Cruz

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23447BDBM23447(Chloromycetin | 2,2-dichloro-N-[(1R,2R)-1,3-dihydr...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of recombinant CYP34A (unknown origin) using fluorogenic substrate in presence of NADPH generating system by fluoroscence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 0 hits for monomerid = 23447