BDBM238363 3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiophene-2-carboxylic acid (1l)

SMILES COc1ccccc1-c1c(sc(SC(C)C)c1C#N)C(O)=O

InChI Key InChIKey=VOZVJNLCCLWQQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238363   

LigandPNGBDBM238363(3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)
Affinity DataIC50: 9.70E+3nMpH: 7.5Assay Description:Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on Wallac Victor fluorimeter from Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
LigandPNGBDBM238363(3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)
Affinity DataIC50: 5.00E+4nMAssay Description:Assays were realized on 96-well plates, as described for yeast FTase but octyl-D-glucopyranoside (0.18%) was used instead of CHAPS and the solution c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre De Recherche De Gif

LigandPNGBDBM238363(3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)
Affinity DataIC50: 3.70E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details Article
PubMed