BDBM238986 US9403846, 3

SMILES C[C@H]1SC(N)=N[C@]2(CO[C@H](C[C@@H]12)C1CC1)c1ccc(F)cc1F

InChI Key InChIKey=HENOYKTZLIYYIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238986   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM238986(US9403846, 3)
Affinity DataIC50: 337nMpH: 4.5Assay Description:A synthetic APP substrate that can be cleaved by beta-secretase having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Gr...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBeta-secretase 2 [21-466](Human)
Pfizer

US Patent
LigandPNGBDBM238986(US9403846, 3)
Affinity DataIC50: 2.49E+3nMpH: 4.5 T: 2°CAssay Description:A synthetic substrate that can be cleaved by BACE2 having N-terminal biotin and made fluorescent by the covalent attachment of Oregon Green at the Cy...More data for this Ligand-Target Pair
In DepthDetails
US Patent