BDBM254823 US9487554, 10

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(ccc34)C(=O)NCC(O)=O)[C@@H]1CC=C2c1cncc(F)c1

InChI Key InChIKey=ZYXRCUIIEKNMBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254823   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM254823(US9487554, 10)
Affinity DataIC50: 1.52E+4nMpH: 7.4Assay Description:The inhibition of CYP17A1 by the test compounds was evaluated using a recombinant enzyme. Human CYP17A1 was expressed in E. coli (Ehmer, P. B. et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
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