BDBM275767 US10071110, Compound CDV::US10071110, Compound Cidofovir(CDV)

SMILES Nc1ccn(CC(CO)OCP(O)(O)=O)c(=O)n1

InChI Key InChIKey=VWFCHDSQECPREK-UHFFFAOYSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 275767   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  1.80E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  460nMAssay Description:Subconfluent human lung fibroblast cells (MRC-5, American Type Culture Collection, Rockville, Md.) in 24-well plates were treated with drugs diluted ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  450nMAssay Description:Antiviral assays for HCMV DNA were carried out by DNA hybridization as reported by Dankner, W. M., Scholl, D., Stanat, S. C., Martin, M., Souke, R. L...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM275767(US10071110, Compound CDV | US10071110, Compound Ci...)
Affinity DataEC50:  2.10E+3nMAssay Description:The activity of cidofovir (CDV), cyclic cidofovir (cCDV), and 1-O-hexadecylpropanediol-3-cCDV (HDP-cCDV) were tested for antiviral activity in human ...More data for this Ligand-Target Pair
In DepthDetails US Patent