BDBM281804 N-(3,4-difluorobenzyl)-2-(((5-(1- methyl-1H-imidazo[4,5-c]quinolin- 8-yl)thiophen-2-yl)methyl)amino)- 5-(trifluoromethyl)nicotinamide::US10030016, Example 2.26

SMILES Cn1cnc2cnc3ccc(cc3c12)-c1ccc(CNc2ncc(cc2C(=O)NCc2ccc(F)c(F)c2)C(F)(F)F)s1

InChI Key InChIKey=VLZCMZHKLMJJDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281804   

Target3-phosphoinositide-dependent protein kinase 1 [51-359](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM281804(N-(3,4-difluorobenzyl)-2-(((5-(1- methyl-1H-imidaz...)
Affinity DataIC50: 100nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair
In DepthDetails
US Patent