BDBM28700 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid::2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid::CHEMBL981::FENOFIBRIC ACID::FIBRICOR::Fenofibrate::LF 153::alpha-1081::procetofenic acid
SMILES CC(C)(C(=O)O)Oc1ccc(cc1)C(=O)c2ccc(cc2)Cl
InChI Key InChIKey=MQOBSOSZFYZQOK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 70 hits for monomerid = 28700
Affinity DataKd: 100nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 10 deg C by fluorimetric assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+5nMAssay Description:Agonist activity at GAL4-tagged human PPARgamma ligand binding domain expressed in human HepG2 cells assessed as receptor transactivation by lucifera...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 2.90E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 42 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.80E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 37 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 420nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 37 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.70E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 30 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 360nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 30 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 94nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 5 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.80E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 5 deg C by fluorimetric assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at GAL4-tagged human PPARalpha ligand binding domain expressed in human HepG2 cells assessed as receptor transactivation by lucifera...More data for this Ligand-Target Pair
Affinity DataKd: 1.90E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 10 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 160nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 15 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.00E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 15 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 20 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.30E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 20 deg C by fluorimetric assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
Affinity DataKd: 2.40E+4nMAssay Description:Binding affinity to rat recombinant L-FABP low affinity site expressed in Escherichia coli BL21(DE3) at 25 deg C by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 340nMAssay Description:Binding affinity to rat recombinant L-FABP high affinity site expressed in Escherichia coli BL21(DE3) at 25 deg C by fluorimetric assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.20E+4nMAssay Description:Partial agonist activity at human PPARalpha expressed in CHO cells co-transfected with Gal4-responsive luciferase reporter plasmid after 24 hrs by tr...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Binding affinity to histidine-tagged human PPARalpha-LBD assessed as recruitment of co-activator peptide fluorescein-labeled PGC1alpha after 2 hrs by...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 9.20E+3nMAssay Description:Agonist activity at human recombinant PPARalpha by transactivation of TK-MH100x4-LUC reporter gene in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARdelta expressed in monkey CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at human PPARalpha expressed in monkey CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARgamma expressed in monkey CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARalpha by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARalpha by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARgamma by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARalpha expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+5nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Agonist activity at PPARalpha (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 2.17E+5nMAssay Description:Agonist activity at human PPARgamma expressed in BHK21 cells assessed as SEAP activity by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxo Wellcome Research & Development
Curated by ChEMBL
Glaxo Wellcome Research & Development
Curated by ChEMBL
Affinity DataEC50: 1.80E+4nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+4nMAssay Description:Compound was tested for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected CV-1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research & Development
Curated by ChEMBL
Glaxo Wellcome Research & Development
Curated by ChEMBL
Affinity DataEC50: 2.50E+5nMAssay Description:Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CV...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.00E+5nMAssay Description:Compound was tested for agonist activity on human Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CV-1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 6.80E+4nMAssay Description:Binding affinity towards human peroxidase proliferator activated receptor alpha (hPPARalpha)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Cotransfection activity of compound against human Peroxisome proliferator activated receptor alpha was determinedMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 3.21E+4nMAssay Description:In vitro transactivation of human Peroxisome proliferator activated receptor alpha (hPPARalpha)More data for this Ligand-Target Pair
Affinity DataEC50: 1.31E+5nMAssay Description:In vitro transactivation of rat Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Mean effective concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor gamma in Gal4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Peroxisome proliferator activated receptor gamma bindingMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro
Curated by ChEMBL
University of Bari Aldo Moro
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+5nMAssay Description:Inhibition of human recombinant COX1 expressed in Sf9 cell microsomes assessed as reduction in conversion of arachidonic acid to PGE2 incubated for 5...More data for this Ligand-Target Pair