BDBM292194 US10100057, Example 49::US11046702, Example 49::US9745310, Example 49

SMILES Fc1ccc(OCc2cn3cc(cnc3n2)-c2ccncc2Cl)cc1

InChI Key InChIKey=YIHOOKSQIMKDFQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 292194   

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292194(US10100057, Example 49 | US9745310, Example 49 | U...)
Affinity DataEC50:  750nMT: 2°CAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292194(US10100057, Example 49 | US9745310, Example 49 | U...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Sk Biopharmaceuticals

US Patent
LigandPNGBDBM292194(US10100057, Example 49 | US9745310, Example 49 | U...)
Affinity DataEC50:  750nMAssay Description:Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...More data for this Ligand-Target Pair
In DepthDetails
US Patent