BDBM299998 N-[(2R)-1- hydroxypropan-2- yl]-6-[4-(4- methoxy-1H- pyrazolo[3,4- b]pyridin-3- yl)piperidin-1-yl]- 2-[{2R)- tetrahydrofuran-2- ylmethoxy] pyrimidine- 4-carboxamide::US9593097, Example 369

SMILES COc1ccnc2[nH]nc(C3CCN(CC3)c3cc(nc(OC[C@H]4CCCO4)n3)C(=O)N[C@H](C)CO)c12

InChI Key

Data  1 KI

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299998   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer Inc

US Patent
LigandPNGBDBM299998(N-[(2R)-1- hydroxypropan-2- yl]-6-[4-(4- methoxy-1...)
Show SMILES COc1ccnc2[nH]nc(C3CCN(CC3)c3cc(nc(OC[C@H]4CCCO4)n3)C(=O)N[C@H](C)CO)c12
Affinity DataKi:  0.0150nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid