BDBM300077 N-(3-amino-3- methylbutan- 2-yl)-2- (cyclo- propylmethoxy)- 6-[4-(4- methoxy-1H- pyrrolo[2,3- b]pyridin-3- yl)piperidin-1- yl]pyrimidine-4- carboxamide::US9593097, Example 457::US9593097, Example 458

SMILES COc1ccnc2[nH]cc(C3CCN(CC3)c3cc(nc(OCC4CC4)n3)C(=O)NC(C)C(C)(C)N)c12

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300077   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300077(N-(3-amino-3- methylbutan- 2-yl)-2- (cyclo- propyl...)
Affinity DataKi: <0.0130nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM300077(N-(3-amino-3- methylbutan- 2-yl)-2- (cyclo- propyl...)
Affinity DataKi:  0.75nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent