BDBM300091 N-[(3R,4S)-4- hydroxytetrahydro- furan-3-yl]-2- {[(2R)-1- methoxypropan-2- yl]oxy}-6-[4-(4- methoxy-1H- pyrrolo[2,3- b]pyridin-3- yl)piperidin-1- yl]pyrimidine-4- carboxamide::US9593097, Example 472

SMILES COC[C@@H](C)Oc1nc(cc(n1)C(=O)N[C@@H]1COC[C@H]1O)N1CCC(CC1)c1c[nH]c2nccc(OC)c12

InChI Key

Data  1 KI

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300091   

TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Pfizer Inc

US Patent
LigandPNGBDBM300091(N-[(3R,4S)-4- hydroxytetrahydro- furan-3-yl]-2- {[...)
Show SMILES COC[C@@H](C)Oc1nc(cc(n1)C(=O)N[C@@H]1COC[C@H]1O)N1CCC(CC1)c1c[nH]c2nccc(OC)c12
Affinity DataKi:  0.0480nMAssay Description:AXL enzyme inhibition (% inhibition, Kiapp and Ki values) by small molecule inhibitors was evaluated using a fluorescence-based microfluidic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid