BDBM313781 US10167292, Example 21

SMILES Cc1nnn2C(CCO)CN(c3ccc(Cl)cc3)c3ccccc3-c12

InChI Key InChIKey=PBZMPCXVZAPRES-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 313781   

TargetBromodomain-containing protein 4(Human)
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313781(US10167292, Example 21)
Affinity DataIC50: 52nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 1 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandPNGBDBM313781(US10167292, Example 21)
Affinity DataIC50: 36nMAssay Description:Inhibition of human His-tagged Brd4 bromodomain 2 expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by addition of biotinyla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2020
Entry Details Article
PubMed