BDBM31788 thieno[2,3-d]pyrimidine deriv., 2k

SMILES CCc1sc2nc(N)[nH]c(=O)c2c1Sc1cccc(Cl)c1

InChI Key InChIKey=QGLSNIDQEFSQHF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 31788   

TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM31788(thieno[2,3-d]pyrimidine deriv., 2k)
Affinity DataIC50: 300nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31788(thieno[2,3-d]pyrimidine deriv., 2k)
Affinity DataIC50: 3.00E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed