BDBM349513 US10207991, Ex. Cpd. No. 28::US10611728, Example Compound 28::US11691947, Example 28

SMILES CC(C)Oc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O

InChI Key InChIKey=CZMKZNSLFDBBJT-UHFFFAOYSA-N

Data  9 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349513   

TargetSigma intracellular receptor 2(Rat)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  11nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Cognition Therapeutics

US Patent
LigandPNGBDBM349513(US10207991, Ex. Cpd. No. 28 | US10611728, Example ...)
Affinity DataKi:  120nMAssay Description:The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent