BDBM35615 pyrazolo pyrimidine, 5u

SMILES C(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1

InChI Key InChIKey=FPEIJQLXFHKLJV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35615   

TargetSerine/threonine-protein kinase mTOR(Human)
Jilin University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 35615BDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR (unknown origin) expressed in HEK293 cells assessed as decrease in phosphorylation of S6K level at Thr389 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed