BDBM35734 sulfonamide deriv., 7b

SMILES NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1

InChI Key InChIKey=FTDLZZRRCJRQAA-UHFFFAOYSA-N

Data  11 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 35734   

TargetCarbonic anhydrase 7(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  6.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  8.30nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  8.30nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  8.60nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  8.60nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  54nM ΔG°:  -9.91kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  54nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  75nM ΔG°:  -9.71kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Istanbul University

LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  75nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  136nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM35734(sulfonamide deriv., 7b)
Affinity DataKi:  212nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed