BDBM367194 5-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-3-carboxamide::US10226452, Example 11

SMILES [O-][N+](=O)c1ccc2oc(=O)n(C(=O)NCCCCc3ccccc3)c2c1

InChI Key InChIKey=ZVMODDKUBIKYMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 367194   

TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367194(5-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human acid ceramidase expressed in HEK293 cells using N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)-4-(2-oxochromen-7-yl)-oxybutyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367194(5-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  3nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent