BDBM370488 1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo[5,1-a]isoindol-5-yl)ethanol;::US10233190, Example 1406

SMILES OC(CC1c2c(cccc2F)-c2cncn12)C1CCC(F)(F)CC1

InChI Key InChIKey=FPKRCRNJVIHTNG-UHFFFAOYSA-N

Data  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 370488   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataEC50:  93nMAssay Description:Inhibition of recombinant human IDO1 expressed in T-REx-293 cells assessed as reduction in kynurenine level measured after 16 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Newlink Genetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 370488BDBM370488(1-(4,4-difluorocyclohexyl)-2-(6-fluoro-5H- imidazo...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed