BDBM393281 US9963439, R116010
SMILES CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C
InChI Key InChIKey=WGVPSTQRQHGEEP-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 393281
TargetCytochrome P450 26A1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 4.30nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 26B1(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 3.10nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 120nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 5.76E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair
TargetCytochrome P450 2C8(Homo sapiens (Human))
University Of Washington Through Its Center For Commercialization
US Patent
University Of Washington Through Its Center For Commercialization
US Patent
Affinity DataIC50: 1.76E+3nMAssay Description:Compounds were assessed for inhibition (IC50, n=2) of CYP2C8, CYP2C9 and CYP3A4 in pooled human liver microsomes using selective probe substrates at ...More data for this Ligand-Target Pair