BDBM418091 (2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol-4-yl)amino]pyrimidin-4- yl}-1-oxo-2,3-dihydro-1H-isoindol-2- yl)-N-[(1S)-1-(3-fluoro-5- methylphenyl)-2- hydroxyethyl]propanamide::US10457669, Example 805::US11001575, Example 805

SMILES C[C@@H](N1Cc2ccc(cc2C1=O)-c1nc(Nc2cnn(C)n2)ncc1Cl)C(=O)N[C@H](CO)c1cc(C)cc(F)c1

InChI Key InChIKey=DVJXZATVQVYDFR-IVZQSRNASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 418091   

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418091((2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50:  1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM418091((2R)-2-(6-{5-chloro-2-[(2-methyl-2H- 1,2,3-triazol...)
Affinity DataIC50:  1.80nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent