BDBM418300 (2R)-2-(6-{5-chloro-2-[(oxan-4- yl)amino]pyrimidin-4-yl}-1-oxo-2,3- dihydro-1H-isoindol-2-yl)-N-[(1S)-1-(3- fluoro-5-hydroxyphenyl)-2- hydroxyethyl]propanamide::US10457669, Example 1105::US11001575, Example 1105
SMILES C[C@@H](N1Cc2ccc(cc2C1=O)-c1nc(NC2CCOCC2)ncc1Cl)C(=O)N[C@H](CO)c1cc(O)cc(F)c1
InChI Key InChIKey=KKLYRZBXJQXIJG-OYLFLEFRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 418300
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair