BDBM418308 (2R)-2-[6-(5-chloro-2-{[cis-3- methoxycyclobutyl]amino}pyrimidin-4- yl)-1-oxo-2,3-dihydro-1H-isoindol-2- yl]-N-[(1S)-1-(3-fluoro-5- methoxyphenyl)-2- hydroxyethyl]propanamide::US10457669, Example 1115::US11001575, Example 1115
SMILES CO[C@@H]1C[C@@H](C1)Nc1ncc(Cl)c(n1)-c1ccc2CN([C@H](C)C(=O)N[C@H](CO)c3cc(F)cc(OC)c3)C(=O)c2c1
InChI Key InChIKey=OLLGJKWLKQRBFO-MVZXKYLFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 418308
Affinity DataIC50: 1.60nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair