BDBM429304 CVD-0006354::acs.jmedchem.1c00409_ST.426::indole chloropyridinyl-ester derived, 1::jm5b01461, Compound 124

SMILES Clc1cncc(OC(=O)c2cccc3[nH]ccc23)c1

InChI Key InChIKey=BOSZJNSICHFHMA-UHFFFAOYSA-N

Data  12 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 429304   

TargetReplicase polyprotein 1ab(2019-nCoV)
Huaqiao University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 429304BDBM429304(jm5b01461, Compound 124 | indole chloropyridinyl-e...)
Affinity DataIC50: 320nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using HiLyte Fluor488TM-ESATLQSGLRKAK-QXL520TM-NH2 as substrate measured after 5 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed