BDBM454519 US10717746, Example 2

SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(Cl)cn1

InChI Key InChIKey=AKIBGBJFUGFCIJ-UHFFFAOYSA-N

Data  13 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454519   

TargetCyclin-dependent kinase 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM454519(US10717746, Example 2)
Affinity DataEC50:  130nMAssay Description:Inhibition of CDK9 in human MV4-11 cells assessed as induction of caspase-3/7 activation measured after 6 hrs followed by Caspase-glo reagent based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed