BDBM454519 US10717746, Example 2

SMILES CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(Cl)cn1

InChI Key InChIKey=AKIBGBJFUGFCIJ-UHFFFAOYSA-N

Data  13 IC50  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 454519   

TargetCyclin-dependent kinase 12(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM454519(US10717746, Example 2)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant N-terminal GST-TEV tagged CDK12 (696 to 1082 residues)/full length human CyclinK expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed