BDBM456914 US10736974, Compound XY-43::US10736974, Entry 17

SMILES OC(=O)CC[C@H](NC(=O)O[C@@H](CCCCNC(=O)c1ccc(I)cc1F)OC=O)C(O)=O

InChI Key InChIKey=WHSXQHNEMYUKGH-HOCLYGCPSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 456914   

TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM456914(US10736974, Compound XY-43 | US10736974, Entry 17)
Affinity DataKi:  0.320nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM456914(US10736974, Compound XY-43 | US10736974, Entry 17)
Affinity DataKi:  0.320nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM456914(US10736974, Compound XY-43 | US10736974, Entry 17)
Affinity DataIC50:  1.60nMAssay Description:The PSMA inhibitory activity was determined using a modification of the fluorescence-based Amplex Red Glutamic Acid Assay. Briefly, lysates of LNCaP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent