BDBM479369 ALP-POS-c59291d4-3::CVD-0006352::ML300-based SC inhibitor 1::US20240239772, Compound ML300::acs.jmedchem.1c00409_ST.352

SMILES c1ccc2c(c1)nnn2CC(=O)N(Cc3ccsc3)c4ccc(cc4)NC(=O)C5CC5

InChI Key InChIKey=OCKMJWOFMCSMEX-UHFFFAOYSA-N

Data  9 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479369   

TargetReplicase polyprotein 1ab(SARS-CoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479369(ML300-based SC inhibitor 1 | ALP-POS-c59291d4-3 | ...)
Affinity DataIC50: 4.45E+3nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM479369(ML300-based SC inhibitor 1 | ALP-POS-c59291d4-3 | ...)
Affinity DataIC50: 4.99E+3nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent