BDBM479369 ALP-POS-c59291d4-3::CVD-0006352::ML300-based SC inhibitor 1::US20240239772, Compound ML300::acs.jmedchem.1c00409_ST.352

SMILES c1ccc2c(c1)nnn2CC(=O)N(Cc3ccsc3)c4ccc(cc4)NC(=O)C5CC5

InChI Key InChIKey=OCKMJWOFMCSMEX-UHFFFAOYSA-N

Data  9 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 479369   

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM479369(ML300-based SC inhibitor 1 | ALP-POS-c59291d4-3 | ...)
Affinity DataIC50: 2.84E+4nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution of Biological Research

LigandPNGBDBM479369(ML300-based SC inhibitor 1 | ALP-POS-c59291d4-3 | ...)
Affinity DataIC50: 3.99E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article

TargetSerine protease 1(Human)
Israel Institution of Biological Research

LigandPNGBDBM479369(ML300-based SC inhibitor 1 | ALP-POS-c59291d4-3 | ...)
Affinity DataIC50: 9.90E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2021
Entry Details Article