BDBM493759 US10988451, Example 229::US11643400, Example 229

SMILES C[C@H]1C\C=C\[C@H](O)[C@@H]2CC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)N=[S@](=O)(NC(=O)c2cc3CO[C@@H](CN4CCN5CCOC[C@H]5C4)Cn3c2)[C@@H]1C

InChI Key InChIKey=CJBOFCYUNJTLPW-CNVIZEBDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493759   

LigandPNGBDBM493759(US10988451, Example 229 | US11643400, Example 229)
Affinity DataIC50:  0.0300nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6×His-Mcl-1 (171...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM493759(US10988451, Example 229 | US11643400, Example 229)
Affinity DataIC50:  0.0300nMAssay Description:The AlphaLISA assay was performed in a 384-well Proxiplate in a total volume of 40 μL. The reaction mixture contained 0.0625 nM 6× His-Mcl-1 (17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent