BDBM50000999 CHEBI:81724::DIMINAZENE

SMILES NC(=N)c1ccc(N\N=N\c2ccc(cc2)C(N)=N)cc1

InChI Key InChIKey=XNYZHCFCZNMTFY-UHFFFAOYSA-N

Data  3 KI  3 IC50

PDB links: 11 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50000999   

TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataKi:  13nMAssay Description:Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cellsMore data for this Ligand-Target Pair
TargetDiamine acetyltransferase 1(Homo sapiens (Human))
Xavier University Of Louisiana

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human SSAT using spermidine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFurin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataKi:  5.42E+3nMAssay Description:Inhibition of furin (unknown origin) using Pyr-RTKR-MCA as substrate incubated for 30 mins and measured by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcid-sensing ion channel 2(Mus musculus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataIC50:  4.52E+4nMAssay Description:Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 2(Mus musculus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataIC50:  1.69E+5nMAssay Description:Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid-sensing ion channel 1(Mus musculus)
Promidis

Curated by ChEMBL
LigandPNGBDBM50000999(CHEBI:81724 | DIMINAZENE)
Affinity DataIC50:  5.69E+4nMAssay Description:Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed