BDBM50005246 1-Phenylpropan-2-amin::1-phenyl-2-aminopropane::1-phenylpropan-2-amine::AMP ASPARTATE::AMPHETAMINE::AMPHETAMINE SULFATE::Amfetamine::Amphetamin::DEXTROAMP SACCHARATE::alpha-methylbenzeneethaneamine::alpha-methylphenylethylamine::amfetaminum::beta-Phenylisopropylamin::beta-aminopropylbenzene::beta-phenylisopropylamine::desoxynorephedrine

SMILES CC(N)Cc1ccccc1

InChI Key InChIKey=KWTSXDURSIMDCE-UHFFFAOYSA-N

Data  47 KI  7 IC50  1 Kd

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50005246   

TargetSolute carrier family 22 member 3(Rat)
Medical College of Georgia

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 4.20E+4nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in OCT3-expressing HRPE cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of noradrenaline transporter in NMRI albino mouse brain assessed as [3H]NA accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of 5-HT transporter in NMRI albino mouse brain assessed as [3H]5-HT accumulation in hypothalamus after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 960nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter expressed in rat striatal homogenate after 5 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [3H]norepinephrine uptake at NET expressed in rat hypothalamic homogenate containing synaptosomes after 5 mins by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCytochrome P450 2A5(Mouse)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibitory concentration against mouse cytochrome P450 2A5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKd:  5.37E+3nMAssay Description:Affinity against serotonergic receptor in the isolated rat stomach fundusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  7.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  24.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  38.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  116nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  992nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  2.41E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  2.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  3.83E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  6.61E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  7.66E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1 receptor of rat prefrontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2018
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  7.66E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]ketanserin from rat 5HT2A expressed in mouse NIH/3T3 cell membranes after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 2 (5-hydroxytryptamine-2) receptor from frontal cortical regions of male Sprague...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]ketanserin from NIH3T3 cells stably expressing rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from A9 cells stably expressing rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2011
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Mouse)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2011
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Chile

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  1.22E+4nMAssay Description:Inhibition of MAOA in rat brain mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005246(beta-aminopropylbenzene | AMPHETAMINE SULFATE | de...)
Affinity DataKi:  4.30E+4nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
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