BDBM50012185 CHEMBL3265230

SMILES O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2c1cccc2Cl

InChI Key InChIKey=FVVYATOWQXNKDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012185   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012185(CHEMBL3265230)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant 5-LO assessed as product formation by cell-free assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012185(CHEMBL3265230)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 2.5 uM A23187 ionophoreMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Friedrich-Schiller-University

Curated by ChEMBL
LigandPNGBDBM50012185(CHEMBL3265230)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of 5-LO in human neutrophils assessed as product formation by cell-intact assay relative to control in presence of 20 uM A23187/AA ionopho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed