BDBM50015538 CHEMBL3265330

SMILES [H][C@@]12COCC[C@@]1([H])[C@]1(COC(N)=N1)c1cc(ccc1O2)-c1cncc(Cl)c1

InChI Key InChIKey=BGRWOLNAPSRJIS-LSBZLQRGSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50015538   

TargetCytochrome P450 2D6(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as amyloid beta production wild type APP expressing by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50015538(CHEMBL3265330)
Affinity DataIC50:  110nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair