BDBM50020874 (3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine::CHEMBL332898

SMILES Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1

InChI Key InChIKey=CEHQLKSLMFIHBF-UHFFFAOYSA-N

Data  2 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50020874   

LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [Ca(2+)]-calmodulin-dependent cGMP-phosphodiesterase 1 from porcine coronary arteriesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against cyclic GMP-phosphodiesterase (PDE V) isolated from porcine aorta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-inhibited phosphodiesterase from porcine coronary arteriesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Pig)
Eisai

Curated by ChEMBL
LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of cAMP specific phosphodiesterase from porcine coronary arteriesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50020874(CHEMBL332898 | (3-Chloro-phenyl)-(4-phenyl-phthala...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cGMP-stimulated phosphodiesterase 2 of porcine coronary arteriesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed