BDBM50021394 CHEMBL3289605

SMILES [NH3+]Cc1ccc(NC(=O)N2C(CC(=O)NCC(O)=O)CC2=O)cc1

InChI Key InChIKey=MLRWZTLJAPFEKW-UHFFFAOYSA-O

Data  10 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021394   

TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataEC50:  763nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataEC50:  763nMAssay Description:Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of fibronectin binding to alpha5beta1 isolated from human K562 cells incubated for 1 hr by scintillation-proximity assay based competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed