BDBM50021394 CHEMBL3289605

SMILES [NH3+]Cc1ccc(NC(=O)N2C(CC(=O)NCC(O)=O)CC2=O)cc1

InChI Key InChIKey=MLRWZTLJAPFEKW-UHFFFAOYSA-O

Data  10 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50021394   

TargetIntegrin alpha-V/beta-5(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataIC50: 104nMAssay Description:Inhibition of fibrinogen binding to alphaVbeta5 isolated form human mCf7 cells incubated for 1 hr by scintillation-proximity assay based competitive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataEC50:  505nMAssay Description:Agonist activity at alphaVbeta5 in human MCF7 cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed