BDBM50021394 CHEMBL3289605

SMILES [NH3+]Cc1ccc(NC(=O)N2C(CC(=O)NCC(O)=O)CC2=O)cc1

InChI Key InChIKey=MLRWZTLJAPFEKW-UHFFFAOYSA-O

Data  10 IC50  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021394   

TargetIntegrin alpha-V/beta-6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of fibronectin binding to alphaVbeta6 isolated form human HT-29 cells incubated for 1 hr by scintillation-proximity assay based competitiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed