BDBM50031472 1,2,3-Trihydroxybenzene, XIV::CHEMBL307145::Pyrogallol (10)::benzene-1,2,3-triol::pyrogallol

SMILES Oc1cccc(O)c1O

InChI Key InChIKey=WQGWDDDVZFFDIG-UHFFFAOYSA-N

Data  15 KI  6 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50031472   

TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) incubated for 2 hrs in presence of staurosporine ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of 8-((4-chlorophenyl)amino)naphthalene-1-sulfonic acid binding to CDK2 (unknown origin) measured after 2 hrs by fluorescence based analys...More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target5-lipoxygenase(Bovine)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer-2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of rat intestinal sucraseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 4(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  490nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  520nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 6(Human)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  520nMAssay Description:Inhibition of human CA6 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  540nMAssay Description:Inhibition of human CA2 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.63E+3nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCarbonic anhydrase(European seabass)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  4.43E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCarbonic anhydrase 6(Human)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  6.83E+3nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  7.35E+3nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  7.41E+3nMAssay Description:Inhibition of human CA1 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50031472(CHEMBL307145 | 1,2,3-Trihydroxybenzene, XIV | pyro...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed