BDBM50038260 2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimidin-4-one::CHEMBL136042

SMILES CC(C)N1C=C(C)C=C2C(=O)NC(N)N=C12

InChI Key InChIKey=CTFGANGSIIDBSJ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038260   

TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  4.40E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  2.30E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  1.80E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  6.00E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed